Bruce L. Miller, MD
A.W. and Mary Margaret Clausen Distinguished Professorship in Neurology & Professor of Psychiatry, UCSF
Director, UCSF Memory and Aging Center
Co-Director, Global Brain Health Institute
UCSF Faculty Profile
Memory and Aging Center Faculty Profile
Key areas: Alzheimer’s disease, behavioral neurology, creativity, frontotemporal dementia
Bruce Miller brings world-renowned expertise in the diagnosis and management of dementia to his role as Co-Director of the Global Brain Health Institute.
Miller studies the underlying mechanisms of neurocognitive disorders and is a world leader in the differential diagnosis of dementia. He holds the A.W. and Mary Margaret Clausen Distinguished Professorship in Neurology at the University of California, San Francisco (UCSF).
Less than two decades ago nearly all cases of dementia were classified as Alzheimer’s disease with little insight into other types of brain disorders. A more recent emphasis on factors such as changes in behavior, language, and mood have led to the discovery and recognition of various neurodegenerative diseases that can be distinguished from one another, making the differential diagnosis of dementia both imperative and identifiable.“I think through the training of a new generation of leaders, we truly have a chance to transform our society.”
Miller is a behavioral neurologist whose work has been devoted to brain and behavior relationships as well as the genetic and molecular underpinnings of disease. His research in frontotemporal dementia (FTD) underlines both the behavioral and emotional deficits that characterize these patients, while simultaneously noting the visual creativity that often develops in the setting of FTD. He has been the principal investigator of the NIH-sponsored Alzheimer’s Disease Research Center (ADRC) and program project on FTD called Frontotemporal Dementia: Genes, Imaging and Emotions for more than 15 years.
His ongoing work includes overseeing a healthy aging study, which includes an artist-in-residence program. In addition, he helps lead two philanthropy-funded research groups, the Tau Consortium and the Consortium for Frontotemporal Research, focused on developing treatments for tau and progranulin disorders, respectively. Miller also works with the National Football League to help educate and assess players regarding traumatic brain injury and the importance of brain health. Most recently, he has helped to lead a groundbreaking supportive care coordination trial to help improve the lives of patients with dementia and their caregivers.
Miller’s extensive knowledge in clinical diagnosis, disease pathology, and brain-behavior relationships make him a widely sought after teacher and mentor. He runs the Behavioral Neurology Fellowship at UCSF, and oversees visits of more than 50 foreign scholars every year. These international collaborations have fostered the development of many new therapeutic approaches, and have pushed researchers worldwide toward a better understanding of FTD and other neurodegenerative diseases.
Bio: Bruce L. Miller holds the A.W. and Mary Margaret Clausen Distinguished Professorship in Neurology at the University of California, San Francisco and directs the UCSF Memory and Aging Center. He is the principal investigator of the NIH-sponsored Alzheimer’s Disease Research Center and program project grant on frontotemporal dementia. In addition, he helps lead the Tau Consortium and the Consortium for Frontotemporal Research, and he works with the National Football League to help with the education and assessment of players related to brain health.
Dr. Miller has been featured in Fortune Magazine, the New York Times, Charlie Rose and PBS Newshour. He has authored more than 750 publications and written The Human Frontal Lobes, The Behavioral Neurology of Dementia, and Frontotemporal Dementia. He has received many awards including the Potamkin Award from the American Academy of Neurology, the Elliot Royer Award from the San Francisco Neurological community, the UCSF Annual Faculty Research Lectureship in Clinical Science, the UCSF Academic Senate Distinction in Mentoring Award, the Gene D. Cohen Research Award in Creativity and Aging from the National Center for Creative Aging, and the 2015 Robert A. Fishman Award and Lecture. In 2016, Dr. Miller was elected to the National Academy of Medicine.
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